Dark sectors 2016 Workshop: community report

This report, based on the Dark Sectors workshop at SLAC in April 2016, summarizes the scientific importance of searches for dark sector dark matter and forces at masses beneath the weak-scale, the status of this broad international field, the important milestones motivating future exploration, and promising experimental opportunities to reach these milestones over the next 5-10 years

Results of the ANCHOR prospective, multicenter registry of EndoAnchors for type Ia endoleaks and endograft migration in patients with challenging anatomy

ObjectiveProximal attachment site complications continue to occur after endovascular repair of abdominal aortic aneurysms (EVAR), specifically type Ia endoleak and endograft migration. EndoAnchors (Aptus Endosystems, Sunnyvale, Calif) were designed to enhance endograft proximal fixation and sealing, and the current study was undertaken to evaluate the potential benefit of this treatment.MethodsDuring the 23-month period ending in December 2013, 319 subjects were enrolled at 43 sites in the United States and Europe. EndoAnchors were implanted in 242 patients (75.9%) at the time of an initial EVAR procedure (primary arm) and in 77 patients with an existing endograft and proximal aortic neck complications (revision arm). Technical success was defined as deployment of the desired number of EndoAnchors, adequate penetration of the vessel wall, and absence of EndoAnchor fracture. Procedural success was defined as technical success without a type Ia endoleak at completion angiography. Values are expressed as mean ± standard deviation and interquartile range.ResultsThe 238 male (74.6%) and 81 female (25.4%) subjects had a mean age of 74.1 ± 8.2 years. Aneurysms averaged 58 ± 13 (51-63) mm in diameter at the time of EndoAnchor implantation (core laboratory measurements). The proximal aortic neck averaged 16 ± 13 (7-23) mm in length (42.7% <10 mm and 42.7% conical) and 27 ± 4 mm (25-30 mm) in diameter; infrarenal neck angulation was 24 ± 15 (13-34) degrees. The number of EndoAnchors deployed was 5.8 ± 2.1 (4-7). Technical success was achieved in 303 patients (95.0%) and procedural success in 279 patients (87.5%), 217 of 240 (89.7%) and 62 of 77 (80.5%) in the primary and revision arms, respectively. There were 29 residual type Ia endoleaks (9.1%) at the end of the procedure. During mean follow-up of 9.3 ± 4.7 months, 301 patients (94.4%) were free from secondary procedures. Among the 18 secondary procedures, eight were performed for residual type Ia endoleaks and the others were unrelated to EndoAnchors. There were no open surgical conversions, there were no aneurysm-related deaths, and no aneurysm ruptured during follow-up.ConclusionsUse of EndoAnchors to treat existing and acute type Ia endoleaks and endograft migration was successful in most cases. Prophylactic use of EndoAnchors in patients with hostile aortic neck anatomy appears promising, but definitive conclusions must await longer term follow-up data

Short-course radiation plus temozolomide in elderly patients with glioblastoma

Glioblastoma is associated with a poor prognosis in the elderly. Survival has been shown to increase among patients 70 years of age or younger when temozolomide chemotherapy is added to standard radiotherapy (60 Gy over a period of 6 weeks). In elderly patients, more convenient shorter courses of radiotherapy are commonly used, but the benefit of adding temozolomide to a shorter course of radiotherapy is unknown

Personality traits and mental disorders

Peer reviewe

Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires

The production of tt‾ , W+bb‾ and W+cc‾ is studied in the forward region of proton–proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fb−1 . The W bosons are reconstructed in the decays W→ℓν , where ℓ denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of $t\overline{t}$, $W+b\overline{b}$ and $W+c\overline{c}$ is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 $\pm$ 0.02 \mbox{fb}^{-1}. The $W$ bosons are reconstructed in the decays $W\rightarrow\ell\nu$, where $\ell$ denotes muon or electron, while the $b$ and $c$ quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions

Observation of the Resonant Character of the Z(4430)(-) State

Resonant structures in B-0 -> psi'pi K--(+) decays are analyzed by performing a four-dimensional fit of the decay amplitude, using pp collision data corresponding to 3 fb(-1) collected with the LHCb detector. The data cannot be described with K+pi(-) resonances alone, which is confirmed with a model-independent approach. A highly significant Z(4430)(-) -> psi'pi(-) component is required, thus confirming the existence of this state. The observed evolution of the Z(4430)(-) amplitude with the psi'pi(-) mass establishes the resonant nature of this particle. The mass and width measurements are substantially improved. The spin parity is determined unambiguously to be 1(+)

Angular moments of the decay Λ _b ⁰ → Λμ⁺μ⁻ at low hadronic recoil

An analysis of the angular distribution of the decay Λ$_{b}^{0}$  → Λμ$^{+}$μ$^{−}$ is presented, using data collected with the LHCb detector between 2011 and 2016 and corresponding to an integrated luminosity of approximately 5 fb$^{−1}$. Angular observables are determined using a moment analysis of the angular distribution at low hadronic recoil, corresponding to the dimuon invariant mass squared range 15 < q$^{2}$ < 20 GeV$^{2}$/c$^{4}$. The full basis of observables is measured for the first time. The lepton-side, hadron-side and combined forward-backward asymmetries of the decay are determined to be \begin{array}{l}{A}_{\mathrm{FB}}^{\ell }=-0.39\pm 0.04\left(\mathrm{stat}\right)\pm 0.01\left(\mathrm{syst}\right),\hfill \\ {}{A}_{\mathrm{FB}}^h=-0.30\pm 0.05\left(\mathrm{stat}\right)\pm 0.02\left(\mathrm{syst}\right),\hfill \\ {}{A}_{\mathrm{FB}}^{\ell h}=+0.25\pm 0.04\left(\mathrm{stat}\right)\pm 0.01\left(\mathrm{syst}\right).\hfill \end{array} An analysis of the angular distribution of the decay $\Lambda_b^0 \rightarrow \Lambda \mu^{+} \mu^{-}$ is presented, using data collected with the LHCb detector between 2011 and 2016 and corresponding to an integrated luminosity of approximately $5\,fb^{-1}$. Angular observables are determined using a moment analysis of the angular distribution at low hadronic recoil, corresponding to the dimuon invariant mass squared range $15 < q^{2} < 20\, GeV^2/c^4$. The full basis of observables is measured for the first time. The lepton-side, hadron-side and combined forward-backward asymmetries of the decay are determined to be \begin{align} A_{FB}^{l} & = -0.39 \pm 0.04\,\rm{stat} \pm 0.01\, \rm{syst}, \nonumber\\ A_{FB}^{h} & = -0.30 \pm 0.05\,\rm{stat} \pm 0.02\, \rm{syst}, \nonumber\\ A_{FB}^{lh} & = +0.25 \pm 0.04\,\rm{stat} \pm 0.01\, \rm{syst}. \nonumber \end{align} The measurements are consistent with Standard Model predictions